Risk factors for prolonged shedding of 2009 H1N1 influenza virus.

Factors promoting the prolonged shedding of the pandemic (H1N1) 2009 influenza virus in patients treated with oseltamivir for 5 days

BACKGROUND The duration of viral shedding is an important determinant of infectivity and transmissibility and provides vital information for effective infection prevention and control. However, few studies have evaluated viral shedding in patients admitted to hospital with 2009 H1N1 influenza and treated with oseltamivir. OBJECTIVE To determine the incidence of prolonged 2009 H1N1 influenza v...

Pathogenic analysis of the pandemic 2009 H1N1 influenza A viruses in ferrets

The pandemic 2009 H1N1 influenza A virus emerged in humans and caused the first influenza pandemic of the 21st century. Mexican isolates, A/Mexico/4108/2009 (H1N1) (Mex4108) and A/Mexico/InDRE4478/2009 (H1N1) (Mex4487) derived from a mild case and from a cluster of severe cases, showed heterogeneity in virulence in a cynomolgus macaque model. To compare the more pathogenic differences, we gener...

2009 H1N1 Influenza Virus Seroepidemiology

یافته‌های دموگرافیک و پاراکلینیکی بیماران مبتلا به آنفلوانزای H1N1 نو پدید بستری در بخش عفونی بیمارستان سینا‌ی تبریز

Background and Objective: Novel H1N1 influenza virus is a unique type of influenza virus which has developed due to abrupt structural alterations (Shift and Drift). This virus can lead to a pandemic disease. Since manifestations and severity of this disease may be affected by environmental, cultural and economic factors, therefore this epidemiological and regional study was carried out to revea...

Phylogenetic Comparison of Influenza Virus Isolates from Three Medical Centers in Tehran with the Vaccine Strains during 2008-2009

Background: Influenza virus is a major infectious pathogen of the respiratory system causing a high degree of morbidity and mortality annually. The worldwide vaccines are decided and produced annually by World Health Organization and licensed companies based on the samples collected from all over the world. The aim of this study was to determine phylogenecity and heterogenecity of the circulati...